Non-surgical periodontal treatment on diabetes management

Summarised from:

The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial
(Journal of Clinical Periodontology; doi: 10.1111/jcpe.12268)

Authors:

Isabel C Gay, Duong T Tran, Adriana C Cavender, Robin Weltman, Jennifer Chang, Estelle Luckenbach, Gena D Tribble

Summarised by:

Dr Dominika Antoniszczak

Research Topic:

Background + Aims

  • Type 2 Diabetes Mellitus (T2DM) is prevalent in Hispanic populations, significantly affected by socioeconomic factors.
  • Periodontitis, a chronic inflammatory disease, has been linked to worsened glycaemic management and increased number of diabetic complications.
  • This study aims to evaluate whether non-surgical periodontal therapy (scaling and root planing (SRP)) improves glycated haemoglobin (HbA1c) levels and periodontal health in Hispanic individuals with T2DM and moderate-to-severe chronic periodontitis.

Materials + Methods

  • Randomised controlled trial (RCT) with 154 participants split equally into a treatment group (SRP and oral hygiene education) and a control group (oral hygiene education only).
  • Inclusion criteria included:
    • Hispanic adults aged ≥18 years
    • Diagnosed with T2DM
    • Moderate-to-severe chronic periodontitis
  • Exclusions included:
    • Recent systemic antibiotic use
    • Recent dental treatment.
  • The experimental group underwent SRP performed by trained periodontists, while controls received oral hygiene education. Periodontal parameters were assessed with calibrated periodontal probes.
  • HbA1c was measured using a standardised boronate affinity assay.
  • Both groups were re-evaluated 4–6 weeks after the baseline and again at 4 months.
  • Outcomes:
    • Primary – change in HbA1c levels at 4 months.
    • Secondary – change in eriodontal parameters, including probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing (BOP).
  • Changes in HbA1c and periodontal parameters were compared using regression analysis and statistical tests, with significance set at p<0.05.

Results

  • A total of 126 participants completed the study.
  • The test and control groups demonstrated no significant differences in baseline characteristics.
  • The reduction in HbA1c levels was greater in the experimental group (0.6%) compared to controls (0.3%), but the difference was not statistically significant.
  • Significant improvements in periodontal health (reduction in PPD, CAL gain, and reduced BOP) were observed in the SRP group compared to controls.
  • Both groups benefited from oral hygiene education, but SRP yielded stronger periodontal improvements.
  • No significant correlation was found between reductions in HbA1c and periodontal parameters.

Limitations

  • The study population was limited to a Hispanic demographic, reducing generalisability.
  • Changes in diet, exercise, or medications during the study may have influenced glycaemic control, introducing potential confounding factors.
  • Baseline variability in HbA1c levels (ranging from 5.7% to 16%) may have impacted results.
  • Periodontal outcomes were assessed over a relatively short period (4–6 weeks), limiting insights into long-term effects.
  • Control subjects demonstrated some periodontal improvements despite no mechanical therapy, likely due to improved oral hygiene practices introduced during the study.

Conclusion

  • Non-surgical periodontal therapy significantly improved periodontal health but did not yield statistically significant improvements in HbA1c levels in Hispanic patients with T2DM. While the study underlines the periodontal benefits of SRP, its impact on glycaemic management  requires further investigation.
  • Incorporating periodontal care into diabetes management protocols may enhance oral health outcomes.
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Research  |  05.05.14

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

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