Research

Diabetes and its effect on peri-implantitis

27.03.17

• Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are common complications affecting dental implants.
• Diabetes mellitus (DM) and hyperglycaemia have been associated with periodontal disease due to their impact on systemic inflammation, poor wound healing, and immune response. However, limited evidence exists on their influence on peri-implant diseases.

Periodontitis and sudden onset diabetes

30.12.16

• Diabetes is a growing global health issue, with an estimated 415 million cases in 2015 and projected to rise to 642 million by 2040.
• Type 2 diabetes mellitus (T2DM) accounts for 90% of cases, posing a significant economic burden, particularly in the UK.

Understanding the link between subgingival microbiome and insulin resistance

15.12.16

Diabetes risk and insulin resistance are associated with chronic systemic inflammation, often exacerbated by microbial factors. Inflammation interferes with insulin signalling, increasing diabetes susceptibility. Periodontitis, a chronic infection of the tooth-supporting structures, is linked to systemic inflammation and glucose intolerance. Emerging research suggests that early microbial changes in the subgingival environment may play a pivotal role in insulin resistance. The study aimed to investigate the relationship between subgingival bacterial composition, systemic inflammation, and insulin resistance in individuals living without diabetes. The hypothesis posited that dysbiosis (bacterial imbalances) in the subgingival microbiome would correlate with elevated inflammation and insulin resistance markers and that systemic inflammation would mediate this relationship. By identifying specific microbial signatures linked to inflammation and glucose regulation, the study hoped to improve early detection of diabetes risks and inform future intervention strategies.

Systemic antimicrobials in periodontal therapy for patients with diabetes

20.01.16

• Diabetes mellitus (DM) is a significant risk factor for periodontitis, particularly in individuals with poor glycaemic control.
• Patients with diabetes exhibit higher prevalence and severity of periodontitis due to mechanisms such as increased infection risk and impaired wound healing.

Periodontitis and mortality in advanced chronic kidney disease

31.12.15

Chronic kidney disease (CKD) affects 8–13% of the global population and is linked to higher mortality, primarily from cardiovascular disease (CVD).Systemic inflammation is a key non-traditional risk factor in CKD.

Predicting molar loss in patients under long-term periodontal care

10.12.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Impact of inflammatory markers on periodontitis progression

16.10.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Increased periodontal bacteria in gestational diabetes

09.05.15

Gestational diabetes mellitus (GDM) and periodontal inflammation are independently associated with adverse pregnancy outcomes, including preterm birth, preeclampsia, and low birth weight.

Pre-diabetes and periodontitis – is there a link?

13.03.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Dental patients identified with hyperglycaemia

28.01.15

Diabetes mellitus (DM) is a significant global health challenge, with Type 2 diabete mellitus (T2DM) often going undiagnosed for years. It is estimated that 46% of diabetes cases worldwide remain undiagnosed, contributing to delayed treatment and increased complications.

Diabetes and its effect on peri-implantitis

27.03.17

• Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are common complications affecting dental implants.
• Diabetes mellitus (DM) and hyperglycaemia have been associated with periodontal disease due to their impact on systemic inflammation, poor wound healing, and immune response. However, limited evidence exists on their influence on peri-implant diseases.

Periodontitis and sudden onset diabetes

30.12.16

• Diabetes is a growing global health issue, with an estimated 415 million cases in 2015 and projected to rise to 642 million by 2040.
• Type 2 diabetes mellitus (T2DM) accounts for 90% of cases, posing a significant economic burden, particularly in the UK.

Understanding the link between subgingival microbiome and insulin resistance

15.12.16

Diabetes risk and insulin resistance are associated with chronic systemic inflammation, often exacerbated by microbial factors. Inflammation interferes with insulin signalling, increasing diabetes susceptibility. Periodontitis, a chronic infection of the tooth-supporting structures, is linked to systemic inflammation and glucose intolerance. Emerging research suggests that early microbial changes in the subgingival environment may play a pivotal role in insulin resistance. The study aimed to investigate the relationship between subgingival bacterial composition, systemic inflammation, and insulin resistance in individuals living without diabetes. The hypothesis posited that dysbiosis (bacterial imbalances) in the subgingival microbiome would correlate with elevated inflammation and insulin resistance markers and that systemic inflammation would mediate this relationship. By identifying specific microbial signatures linked to inflammation and glucose regulation, the study hoped to improve early detection of diabetes risks and inform future intervention strategies.

Systemic antimicrobials in periodontal therapy for patients with diabetes

20.01.16

• Diabetes mellitus (DM) is a significant risk factor for periodontitis, particularly in individuals with poor glycaemic control.
• Patients with diabetes exhibit higher prevalence and severity of periodontitis due to mechanisms such as increased infection risk and impaired wound healing.

Periodontitis and mortality in advanced chronic kidney disease

31.12.15

Chronic kidney disease (CKD) affects 8–13% of the global population and is linked to higher mortality, primarily from cardiovascular disease (CVD).Systemic inflammation is a key non-traditional risk factor in CKD.

Predicting molar loss in patients under long-term periodontal care

10.12.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Impact of inflammatory markers on periodontitis progression

16.10.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Increased periodontal bacteria in gestational diabetes

09.05.15

Gestational diabetes mellitus (GDM) and periodontal inflammation are independently associated with adverse pregnancy outcomes, including preterm birth, preeclampsia, and low birth weight.

Pre-diabetes and periodontitis – is there a link?

13.03.15

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Dental patients identified with hyperglycaemia

28.01.15

Diabetes mellitus (DM) is a significant global health challenge, with Type 2 diabete mellitus (T2DM) often going undiagnosed for years. It is estimated that 46% of diabetes cases worldwide remain undiagnosed, contributing to delayed treatment and increased complications.