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Research Hub

Welcome to the Research Hub – your go-to source for concise, digestible summaries of the latest research on the connection between periodontitis and diabetes. Explore key findings on topics such as how periodontal inflammation affects glycaemic control and the benefits of periodontal treatment.

Our summaries provide quick insights, but they are not exhaustive. For a complete understanding of each study’s methodology, results, and implications, we encourage you to review the original research articles. Please note that the Periodontitis-Diabetes hub is not responsible for inaccuracies or misinterpretations of condensed content.

For more guidance on understanding research, including how to interpret studies and evaluate their findings, visit the Colgate StuDENT App and search for ‘Understanding Research in Dentistry.’

Dive into the science and uncover the powerful link between oral and systemic health!

Featured posts

Periodontal condition and type 2 diabetes risk: 15-year follow-up results

22.08.18

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterised by insulin resistance and elevated blood glucose levels, influenced by factors like obesity and inflammation.

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One-stage versus quadrant-by-quadrant non-surgical periodontal therapy in type 2 diabetes

19.07.18

Patients with type 2 diabetes mellitus (T2DM) exhibit higher prevalence and severity of chronic periodontitis compared to individuals without diabetes.
Non-surgical periodontal therapy (NSPT), including scaling and root planing (SRP), has been suggested to improve glycaemic control in T2DM patients.

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Impact of glycaemic status on the subgingival microbiome in diabetes

09.05.18

The human microbiome plays a vital role in health, with links between gut microbiota and metabolic disorders like type 2 diabetes mellitus (T2DM).The oral microbiota, particularly the subgingival microbiome, is thought to be influenced by diabetes.

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Periodontal disease and gestational diabetes: a prospective cohort study

03.04.18

Gestational diabetes mellitus (GDM) is a carbohydrate intolerance which begins during pregnancy, with Indian women at significantly higher risk (approximately 11-fold) compared to Caucasians.

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Analysis of systemic inflammation on the link between periodontitis and glycaemic status

03.03.18

  • Emerging evidence suggests that periodontitis may increase the risk of developing type 2 diabetes.
  • Cross-sectional studies, such as NHANES III in the US and KNHANES in Korea, have shown that periodontitis is associated with impaired fasting glucose and diabetes.
  • Prospective studies in the US, Germany, and Japan further confirmed that individuals with periodontitis have poorer glycaemic control and higher risk of diabetes.
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Periodontitis and retinal vessel health

31.01.18

Chronic periodontitis is a common inflammatory disease that causes progressive bone loss and, if untreated, can lead to tooth loss.

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Non-surgical periodontal treatment benefits people living with diabetes

19.12.17

  • Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
  • Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.
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Prevalence of diabetes in people with periodontitis

10.11.17

Periodontitis is a widespread condition affecting over half of the global adult population, with prevalence increasing with age.Severe periodontitis is one of the most common human diseases, contributing significantly to tooth loss.

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Periodontal treatment and improved glycaemic management among elderly individuals

23.07.17

Diabetes mellitus (DM), particularly type 2 (T2DM), is prevalent in the elderly and associated with complications like neuropathy, retinopathy, and cardiovascular issues. Poor glycaemic management exacerbates these complications, significantly affecting quality of life. Periodontitis, a chronic inflammatory disease of the gums, is common in individuals with T2DM. Research indicates a two-way relationship: Periodontitis worsens gum health, while DM elevates systemic inflammation, impairing blood glucose control. In Japan, over half the population aged 40+ years experiences periodontitis. Addressing periodontitis could potentially improve glycaemic management in people with T2DM. This study aimed to assess whether dental visits for periodontal treatment correlate with improved diabetes outcomes in an elderly Japanese cohort.

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Cost-effectiveness of treating periodontitis in patients with diabetes

23.06.17

There is increasing evidence linking periodontal inflammation to elevated glycated haemoglobin (HbA1c) levels in patients with type 2 diabetes mellitus (T2DM). Periodontal disease is more prevalent in those with T2DM and contributes to chronic inflammation, potentially raising HbA1c levels. Persistently high HbA1c can lead to severe complications such as cardiovascular disease, blindness, amputations, renal failure, and premature death.

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Periodontitis is the 6th most prevalent condition globally

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Periodontitis and diabetes are bidirectionally linked

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Diabetic complications are increased if you have both diseases

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Successful periodontal treatment can improve blood glucose control

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Successful periodontal treatment can improve blood glucose control

icon1 services

Periodontitis is the 6th most prevalent condition globally

icon1 services

Periodontitis and diabetes are bidirectionally linked

icon1 services

Diabetic complications are increased if you have both diseases

icon1 services

Successful periodontal treatment can improve blood glucose control

icon1 services

Successful periodontal treatment can improve blood glucose control

Our Team

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Education & Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Outreach & Communications Lead

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

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