Research

Inflammatory cell death exaggerates periodontal inflamm-ageing

18.08.21

Diabetes mellitus (DM) accelerates periodontal disease through hyperglycaemia-induced inflamm-ageing, a chronic, low-grade inflammatory state driven by cellular senescence and the senescence-associated secretory phenotype (SASP). Inflamm-aging disrupts gingival defence mechanisms, including epithelial and fibroblast resistance and immune responses to infection.

Predictors of tooth loss during periodontal maintenance

17.05.21

Periodontal maintenance (PM) is crucial for preventing the progression of periodontitis and minimising tooth loss after active periodontal treatment (APT). It includes tailored care such as oral hygiene education, scaling, root planing, and tooth polishing. Despite advances in periodontal therapy, factors like age, smoking, diabetes, and compliance with PM visits impact treatment outcomes.

Tailored periodontal maintenance preserves teeth in high-risk cases

16.05.21

Periodontitis is a chronic inflammatory disease causing tissue destruction and tooth loss, often requiring lifelong management. Regular maintenance, termed supportive periodontal therapy (SPT), plays a crucial role in preventing disease progression. The World Workshop (2017) introduced a multidimensional classification for periodontitis, categorising cases into stages (severity) and grades (rate of progression). This study aims to evaluate how the regularity of maintenance visits impacts tooth loss related to periodontitis (TLP) based on staging and grading. It hypothesises that higher disease severity (stages III/IV) and rapid progression (grade C) increase susceptibility to tooth loss, especially with inconsistent maintenance.

How periodontal management affects diabetes healthcare costs and outcomes

05.02.21

Periodontitis and type 2 diabetes are linked through a bidirectional relationship: diabetes increases the risk and severity of periodontitis, while periodontal inflammation worsens glycaemic control.
Systemic inflammation, driven by cytokines, contributes to complications such as cardiovascular disease and stroke. Associations between severe periodontitis and cardiovascular diseases have also been well-established.

Dental visits can detect hyperglycaemia

21.12.20

Diabetes mellitus (DM) is a prevalent chronic condition, often undiagnosed, and associated with significant morbidity. Periodontitis is a chronic gum disease linked to systemic inflammation, and dental settings have been proposed as a location for screening undiagnosed DM and prediabetes.

Salivary biomarkers to detect gum disease in people living with diabetes

23.10.20

Periodontitis, a chronic gum disease, involves inflammation and tissue destruction. It is especially common in people living with diabetes, making diagnosis and monitoring crucial.

Hyperglycaemia and periodontal status amongst the 1966 Northern Finland birth cohort

13.10.20

• Prediabetes, a precursor to diabetes mellitus, is marked by elevated fasting plasma glucose levels below the diabetes threshold.
• Its prevalence varies based on diagnostic criteria and population characteristics, affecting nearly half of Asian and European Caucasian adults.

Bias analysis of confounding factors between diabetes and periodontitis

08.10.20

Periodontitis has been linked to various systemic diseases, including diabetes, cardiovascular disease, and rheumatoid arthriti

Periodontitis misclassification bias and its impact on diabetes and CVD associations

29.09.20

Partial-mouth protocols (PMPs) are commonly used in population health studies to estimate periodontal disease prevalence, offering a cost-effective and time-efficient alternative to full-mouth protocols (FMPs). However, PMPs are known to underestimate periodontal disease prevalence, which may lead to biases in studies examining associations between periodontitis and systemic conditions like diabetes and cardiovascular disease (CVD).

Dental insurance and mortality in US adults with periodontitis

16.09.20

Periodontitis, a chronic inflammatory disease caused by bacterial plaque, is associated with systemic conditions such as cardiovascular diseases, diabetes, and adverse pregnancy outcomes. It has also been linked to increased mortality risks

Inflammatory cell death exaggerates periodontal inflamm-ageing

18.08.21

Diabetes mellitus (DM) accelerates periodontal disease through hyperglycaemia-induced inflamm-ageing, a chronic, low-grade inflammatory state driven by cellular senescence and the senescence-associated secretory phenotype (SASP). Inflamm-aging disrupts gingival defence mechanisms, including epithelial and fibroblast resistance and immune responses to infection.

Predictors of tooth loss during periodontal maintenance

17.05.21

Periodontal maintenance (PM) is crucial for preventing the progression of periodontitis and minimising tooth loss after active periodontal treatment (APT). It includes tailored care such as oral hygiene education, scaling, root planing, and tooth polishing. Despite advances in periodontal therapy, factors like age, smoking, diabetes, and compliance with PM visits impact treatment outcomes.

Tailored periodontal maintenance preserves teeth in high-risk cases

16.05.21

Periodontitis is a chronic inflammatory disease causing tissue destruction and tooth loss, often requiring lifelong management. Regular maintenance, termed supportive periodontal therapy (SPT), plays a crucial role in preventing disease progression. The World Workshop (2017) introduced a multidimensional classification for periodontitis, categorising cases into stages (severity) and grades (rate of progression). This study aims to evaluate how the regularity of maintenance visits impacts tooth loss related to periodontitis (TLP) based on staging and grading. It hypothesises that higher disease severity (stages III/IV) and rapid progression (grade C) increase susceptibility to tooth loss, especially with inconsistent maintenance.

How periodontal management affects diabetes healthcare costs and outcomes

05.02.21

Periodontitis and type 2 diabetes are linked through a bidirectional relationship: diabetes increases the risk and severity of periodontitis, while periodontal inflammation worsens glycaemic control.
Systemic inflammation, driven by cytokines, contributes to complications such as cardiovascular disease and stroke. Associations between severe periodontitis and cardiovascular diseases have also been well-established.

Dental visits can detect hyperglycaemia

21.12.20

Diabetes mellitus (DM) is a prevalent chronic condition, often undiagnosed, and associated with significant morbidity. Periodontitis is a chronic gum disease linked to systemic inflammation, and dental settings have been proposed as a location for screening undiagnosed DM and prediabetes.

Salivary biomarkers to detect gum disease in people living with diabetes

23.10.20

Periodontitis, a chronic gum disease, involves inflammation and tissue destruction. It is especially common in people living with diabetes, making diagnosis and monitoring crucial.

Hyperglycaemia and periodontal status amongst the 1966 Northern Finland birth cohort

13.10.20

• Prediabetes, a precursor to diabetes mellitus, is marked by elevated fasting plasma glucose levels below the diabetes threshold.
• Its prevalence varies based on diagnostic criteria and population characteristics, affecting nearly half of Asian and European Caucasian adults.

Bias analysis of confounding factors between diabetes and periodontitis

08.10.20

Periodontitis has been linked to various systemic diseases, including diabetes, cardiovascular disease, and rheumatoid arthriti

Periodontitis misclassification bias and its impact on diabetes and CVD associations

29.09.20

Partial-mouth protocols (PMPs) are commonly used in population health studies to estimate periodontal disease prevalence, offering a cost-effective and time-efficient alternative to full-mouth protocols (FMPs). However, PMPs are known to underestimate periodontal disease prevalence, which may lead to biases in studies examining associations between periodontitis and systemic conditions like diabetes and cardiovascular disease (CVD).

Dental insurance and mortality in US adults with periodontitis

16.09.20

Periodontitis, a chronic inflammatory disease caused by bacterial plaque, is associated with systemic conditions such as cardiovascular diseases, diabetes, and adverse pregnancy outcomes. It has also been linked to increased mortality risks