Research

Elevated enzyme activity in periodontitis and diabetes

20.10.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Cholesterol levels and periodontal inflammation in type 1 diabetes

09.10.11

Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth, leading to progressive periodontal tissue destruction and eventual tooth loss if untreated. The main aetiological factor for periodontitis is plaque. However, the two main risk factors for progression of the disease have been identified as smoking and diabetes.

Oxidative stress and inflammatory status in type 2 diabetes with periodontitis

24.08.11

Periodontitis is a chronic inflammatory disease affecting tooth-supporting tissues, driven by pathogenic plaque biofilm and a hyper-inflammatory host response. It leads to periodontal pocket formation, tissue destruction, and potential tooth loss. Individuals with Type 2 diabetes face an increased risk and severity of periodontitis due to their predisposition to oxidative stress and inflammation.

The role of inflammatory mediators in periodontal inflammation in type 1 diabetes

19.04.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal treatment on diabetes care

29.11.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Is there a connection between insulin resistance and periodontitis in a non-diabetic population?

10.11.10

Insulin resistance, a condition where cells fail to respond effectively to insulin, is central to metabolic disorders like type 2 diabetes and cardiovascular disease. It often leads to systemic low-grade inflammation, a feature shared with periodontal disease, suggesting a potential biological link between these conditions.

Cytokine levels in periodontitis among type 2 diabetes patients

28.09.10

Periodontitis and diabetes share a bidirectional relationship, where poor glycaemic control exacerbates periodontal disease and vice versa. The interplay between periodontal inflammation and glycaemic status is mediated by immune cells, primarily T-helper (Th) cells, which regulate pro- and anti-inflammatory cytokine production.

Periodontitis, blood pressure, and cardiovascular risk in people living with type 2 diabetes

12.07.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal progression and glycaemic control in Gullah African Americans

14.05.10

Periodontal disease and type 2 diabetes mellitus (T2DM) are interrelated, with evidence suggesting that periodontal disease worsens diabetic control and, conversely, that managing periodontal disease can improve glycaemic control. The host inflammatory response plays a key role in increasing susceptibility to periodontal disease, particularly in individuals with systemic conditions like T2DM. Studies show that individuals with severe periodontitis experience more diabetes-related complications and have poorer HbA1c levels over time. The Gullah population of coastal South Carolina and Georgia, descendants of enslaved Africans, is particularly affected by T2DM due to their genetic predisposition and social isolation. The Gullah have a higher prevalence of chronic diseases, including obesity and hypertension, compared to other populations. Notably, periodontal disease is more prevalent among Gullah individuals with T2DM (70.6%) compared to national estimates for African Americans with diabetes (31.3%). This study aimed to explore the relationship between glycaemic control and periodontal disease progression in Gullah individuals with T2DM.

Periodontal health in urban Sri Lankans with type 2 diabetes

07.01.10

Diabetes poses a significant public health burden globally, with prevalence expected to rise sharply, especially in urbanizing areas of developing countries.

Elevated enzyme activity in periodontitis and diabetes

20.10.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Cholesterol levels and periodontal inflammation in type 1 diabetes

09.10.11

Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth, leading to progressive periodontal tissue destruction and eventual tooth loss if untreated. The main aetiological factor for periodontitis is plaque. However, the two main risk factors for progression of the disease have been identified as smoking and diabetes.

Oxidative stress and inflammatory status in type 2 diabetes with periodontitis

24.08.11

Periodontitis is a chronic inflammatory disease affecting tooth-supporting tissues, driven by pathogenic plaque biofilm and a hyper-inflammatory host response. It leads to periodontal pocket formation, tissue destruction, and potential tooth loss. Individuals with Type 2 diabetes face an increased risk and severity of periodontitis due to their predisposition to oxidative stress and inflammation.

The role of inflammatory mediators in periodontal inflammation in type 1 diabetes

19.04.11

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal treatment on diabetes care

29.11.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Is there a connection between insulin resistance and periodontitis in a non-diabetic population?

10.11.10

Insulin resistance, a condition where cells fail to respond effectively to insulin, is central to metabolic disorders like type 2 diabetes and cardiovascular disease. It often leads to systemic low-grade inflammation, a feature shared with periodontal disease, suggesting a potential biological link between these conditions.

Cytokine levels in periodontitis among type 2 diabetes patients

28.09.10

Periodontitis and diabetes share a bidirectional relationship, where poor glycaemic control exacerbates periodontal disease and vice versa. The interplay between periodontal inflammation and glycaemic status is mediated by immune cells, primarily T-helper (Th) cells, which regulate pro- and anti-inflammatory cytokine production.

Periodontitis, blood pressure, and cardiovascular risk in people living with type 2 diabetes

12.07.10

• Diabetes mellitus (DM) is associated with severe systemic and oral health complications, including periodontitis, which is characterised by gum inflammation, periodontal tissue damage, and tooth loss.
• Pre-diabetes, a metabolic condition with elevated blood glucose levels below the diabetic threshold, is also linked to complications like nephropathy and neuropathy.

Periodontal progression and glycaemic control in Gullah African Americans

14.05.10

Periodontal disease and type 2 diabetes mellitus (T2DM) are interrelated, with evidence suggesting that periodontal disease worsens diabetic control and, conversely, that managing periodontal disease can improve glycaemic control. The host inflammatory response plays a key role in increasing susceptibility to periodontal disease, particularly in individuals with systemic conditions like T2DM. Studies show that individuals with severe periodontitis experience more diabetes-related complications and have poorer HbA1c levels over time. The Gullah population of coastal South Carolina and Georgia, descendants of enslaved Africans, is particularly affected by T2DM due to their genetic predisposition and social isolation. The Gullah have a higher prevalence of chronic diseases, including obesity and hypertension, compared to other populations. Notably, periodontal disease is more prevalent among Gullah individuals with T2DM (70.6%) compared to national estimates for African Americans with diabetes (31.3%). This study aimed to explore the relationship between glycaemic control and periodontal disease progression in Gullah individuals with T2DM.

Periodontal health in urban Sri Lankans with type 2 diabetes

07.01.10

Diabetes poses a significant public health burden globally, with prevalence expected to rise sharply, especially in urbanizing areas of developing countries.