Topic:

Haemoglobin A1c (HbA1c):

This test gives an average of blood glucose levels over the past 2-3 months. It is often used to diagnose and monitor diabetes.

UK Other countries
mmol/mol % mmol/mol %
Normal <42 <6.0 <39 <5.7
Pre-diabetes 42 – 47 6.0 – 6.4 39 – 47 5.7 – 6.4
Diabetes ≥48 ≥6.5 ≥48 ≥6.5

Normal blood glucose levels:

mmol/L mg/dL
Fasting blood glucose (after at least 8 hours of no eating): 3.9 – 5.5 70 – 99
Postprandial (2 hours after eating) <7.8 <140
Random (anytime of day): <7.8 <140

Though this depends on timings in relation to meals and may vary depending on various contexts. Therefore, it needs to be assessed with a trained clinician.

Pre-diabetes:

This is an intermediate stage where blood glucose is higher than normal but not yet high enough to be classified as diabetes.

mmol/L mg/dL
Impaired fasting blood glucose (after at least 8 hours of no eating): 6.1 – 6.9* 110 – 125
Impaired glucose tolerance (fasting glucose) <7.0 <126
Impaired glucose tolerance (postprandial – 2 hours after eating) 7.8 – 11.0 140 – 199

*As defined by World Health Organization but thresholds may vary across different countries.

Diabetes:

A diagnosis of diabetes is made when blood glucose levels are consistently above the normal range.

mmol/L mg/dL
Fasting blood glucose (after at least 8 hours of no eating): ≥7.0 ≥126
Postprandial (2 hours after eating) ≥11.1 ≥200

Complications of diabetes:

mmol/L mg/dL
Hypoglycemia (low blood glucose):

  • Symptoms may include shakiness, sweating, confusion, dizziness, and fatigue.
  • Severe hypoglycemia can lead to loss of consciousness and requires immediate treatment.
≤3.9 <70
Hyperglycemia (high blood glucose)

  • Symptoms may include increased thirst, frequent urination, fatigue, blurred vision, and slow wound healing.
>10.0 >180

Important points:

  • Time of day and when you last ate can significantly influence blood glucose levels, so these factors must be considered when interpreting the results.
  • Individual variation exists, so a healthcare provider should interpret your results based on your medical history and other factors.
  • Regular monitoring is essential for managing blood glucose, especially for people with diabetes or pre-diabetes.

References:

World Health Organization (WHO) (2006) Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia. Available at: https://www.who.int/publications/i/item/definition-and-diagnosis-of-diabetes-mellitus-and-intermediate-hyperglycaemia
World Health Organization (WHO) (2011) Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus. Available at: https://www.who.int/publications/i/item/use-of-glycated-haemoglobin-(-hba1c)-in-diagnosis-of-diabetes-mellitus
Diabetes UK. New diagnostic criteria for diabetes. Available at: https://www.diabetes.org.uk/for-professionals/improving-care/clinical-recommendations-for-professionals/diagnosis-ongoing-management-monitoring/new_diagnostic_criteria_for_diabetes
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Written By : Dr Amar Puttanna

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