Topic:

Did you know that periodontitis (irreversible gum disease) can have an impact on your overall health?

Periodontitis is a chronic inflammatory condition associated with a dysbiotic (unbalanced) plaque biofilm. It is thought to play a role on your general health through 2 key pathways: the spread of bacteria and increased inflammation in the body.

How bacteria from periodontitis can spread

  • In a healthy mouth, the gums and the immune system stop bacteria from spreading into the bloodstream.
  • When the gums become inflamed and damaged by periodontitis, bacteria can enter the bloodstream more easily.
  • Once bacteria from the mouth get into the bloodstream, they can spread to other parts of the body and may contribute to infections in distant areas.
  • Simple actions like brushing your teeth or chewing can also allow bacteria to enter the bloodstream. These usually do not cause issues, but in some cases these bacteria may stay in the body and lead to more inflammation

Systemic inflammation

  • When your gums are inflamed, they release molecules which enter the bloodstream and cause a wider immune response in the body.
  • These molecules can cause your body to produce more white blood cells, which are part of your immune system.
  • Over time, the bacteria and their by-products can form immune complexes which can settle in different parts of the body, causing more inflammation and potentially damaging tissues.

Associations with systemic diseases

Research has shown that periodontitis is associated with several serious health conditions, including:

  • Adverse pregnant outcomes (e.g. premature birth, low birth weight)
  • Heart disease
  • Chronic kidney disease
  • Chronic obstructive pulmonary disease (COPD)
  • Cognitive impairment
  • COVID-19 complications
  • Diabetes
  • Metabolic syndrome
  • Obesity
  • Sleep apnoea
  • Pneumonia
  • Rheumatoid arthritis

It is important to understand that while periodontitis is linked to these health conditions, this does not mean that periodontitis causes all of them directly. More research is needed to fully understand these connections. However, managing your gum health is an important part of keeping your whole body healthy. By keeping your gums healthy through regular dental care, you may help reduce your risk of some systemic health problems.

References

Van Dyke TE, van Winkelhoff AJ. Infection and inflammatory mechanisms. J Clin Periodontol. 2013 Apr;40 Suppl 14:S1-7. doi: 10.1111/jcpe.12088. PMID: 23627321.
Linden GJ, Herzberg MC; Working group 4 of joint EFP/AAP workshop. Periodontitis and systemic diseases: a record of discussions of working group 4 of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Clin Periodontol. 2013 Apr;40 Suppl 14:S20-3. doi: 10.1111/jcpe.12091. PMID: 23627330.
Herrera D, Sanz M, Shapira L, Brotons C, Chapple I, Frese T, Graziani F, Hobbs FDR, Huck O, Hummers E, Jepsen S, Kravtchenko O, Madianos P, Molina A, Ungan M, Vilaseca J, Windak A, Vinker S. Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: Consensus report of the Joint Workshop by the European Federation of Periodontology (EFP) and the European arm of the World Organization of Family Doctors (WONCA Europe). J Clin Periodontol. 2023 Jun;50(6):819-841. doi: 10.1111/jcpe.13807. Epub 2023 Mar 22. PMID: 36935200.
Back to Clinic Knowledge

Clinical knowledge summaries

clock icon 5 mins to read
tag iconPeriodontitis
Written By : Dr Varkha Rattu

Share this page:

Copy Link
Download PDF

You might also like...

Events

Oral Health Challenges Among People Living With Diabetes

Dr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on…

Read more

Events

Periodontitis-Diabetes Hub x #DiabetesChat

Hosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.

Read more

Events

Oral Health Challenges Among People Living With Diabetes

Dr Antoniszczak will present a lecture about the oral health challenges among people living with diabetes. This lecture explores the key challenges faced by individuals living with diabetes, focusing on…

Read more

Events

Periodontitis-Diabetes Hub x #DiabetesChat

Hosted by #diabeteschat, join Dr Varkha Rattu and the team behind the Periodontitis-Diabetes Hub for an insightful discussion exploring the importance of managing periodontitis and diabetes.

Read more
icon1 services

Chronic inflammation links both diseases

icon1 services

Periodontitis can significantly increase blood glucose levels

icon1 services

Inflammation from periodontitis exacerbates insulin resistance

icon1 services

Regular periodontal reviews can aid diabetes management

icon1 services

Chronic inflammation links both diseases

icon1 services

Periodontitis can significantly increase blood glucose levels

icon1 services

Inflammation from periodontitis exacerbates insulin resistance

icon1 services

Regular periodontal reviews can aid diabetes management

Our Team

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Education & Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Outreach & Communications Lead

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

View All