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A growing body of research suggests that periodontitis (irreversible gum disease) may contribute to the development of new cases of type 2 diabetes and possibly gestational diabetes (a type of diabetes that develops during pregnancy in individuals who did not previously have diabetes).

Can periodontitis increase blood glucose (sugar) levels?

Studies show that even in healthy individuals without diabetes, periodontitis is linked to higher blood glucose levels compared to people with little or no periodontitis. This suggests that gum disease may:

  • Increase the risk of developing diabetes in otherwise healthy individuals.
  • Make it harder to control blood sugar in people who already have diabetes.

One important study found that individuals with both diabetes and severe periodontitis had worse blood sugar control over a 2-year period compared to those with diabetes but milder periodontitis. This highlights that having both severe periodontitis and diabetes can worsen diabetes symptoms and increase the risk of diabetic complications.

How does periodontitis affect blood glucose levels?

Gum disease starts with plaque biofilm on the teeth. When this is not removed, it leads to inflammation in the gums and the breakdown of tissue and bone that support your teeth. In individuals with periodontitis, and even more so in people with both diabetes and periodontitis, this leads to:

  • Inflammation from periodontitis spreading to the bloodstream.
  • This inflammation contributes to insulin resistance, making it harder for your body to control blood sugar levels.
  • High blood glucose levels then trigger pathways that increase inflammation, making both periodontitis and diabetes worse.
  • This creates a vicious cycle, where periodontitis makes it harder to manage diabetes, and poorly controlled diabetes makes periodontitis more severe.

Why managing periodontitis is important for people with and without diabetes

Looking after your gum health is a key part of managing your overall health. By reducing inflammation, treating periodontitis can help improve blood glucose control and lower the risk of diabetic complications (especially those affecting blood vessels such as heart disease, kidney disease, and eye problems). Taking care of your mouth and body together can make a positive difference to your long-term health.

References

Genco RJ, Graziani F, Hasturk H. Effects of periodontal disease on glycemic control, complications, and incidence of diabetes mellitus. Periodontol 2000. 2020 Jun;83(1):59-65. doi: 10.1111/prd.12271. PMID: 32385875.
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tag iconPeriodontitis,Diabetes
Written By : Dr Varkha Rattu

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Chronic inflammation links both diseases

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Periodontitis can significantly increase blood glucose levels

icon1 services

Inflammation from periodontitis exacerbates insulin resistance

icon1 services

Regular periodontal reviews can aid diabetes management

icon1 services

Chronic inflammation links both diseases

icon1 services

Periodontitis can significantly increase blood glucose levels

icon1 services

Inflammation from periodontitis exacerbates insulin resistance

icon1 services

Regular periodontal reviews can aid diabetes management

Our Team

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Education & Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Outreach & Communications Lead

Team - The Periodontitis-Diabetes Hub

Dr Varkha Rattu

Periodontitis-Diabetes Hub Position: Founder & Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Amar Puttanna

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Rajeev Raghavan

Periodontitis-Diabetes Hub Position: Diabetes Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Mark Ide

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Professor Luigi Nibali

Periodontitis-Diabetes Hub Position: Periodontology Co-Lead

Team - The Periodontitis-Diabetes Hub

Dr Dominika Antoniszczak

Periodontitis-Diabetes Hub Position: Education and Support Advisor

Team - The Periodontitis-Diabetes Hub

Dr Jasmine Loke

Periodontitis-Diabetes Hub Position: Clinical Content Advisor

Team - The Periodontitis-Diabetes Hub

Dr Mira Shah

Periodontitis-Diabetes Hub Position: Patient Resource Advisor

Team - The Periodontitis-Diabetes Hub

Elaine Tilling

Periodontitis-Diabetes Hub Position: Outreach and Communications Lead

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